Vouchers are special items found in the shop that provide permanent, run-long benefits. Unlike Jokers, they don't take up a slot and their effects are passive. They can offer crucial advantages like increased money from blinds, more shop rerolls, or discounts on items. Prioritize buying Vouchers when they appear, especially early in a run, as their benefits accumulate over time. They are a significant investment but often pay for themselves quickly.

Common Voucher effects include:
- Increased Money: Gain more money from clearing blinds.
- Shop Discounts: Reduce the cost of items in the shop.
- More Rerolls: Increase the number of shop rerolls available.
- Extra Joker Slots: Permanently increase your maximum Joker slots.