Balatro features several unlockable decks, each with a unique starting bonus or ability. These decks can significantly alter your starting strategy and open up new build possibilities. Unlocking them usually involves achieving specific milestones, such as winning a run with a certain deck, reaching a high score, or completing a challenge run. Experimenting with different decks is crucial for discovering new powerful synergies and finding your preferred playstyle.

Each deck offers a distinct advantage:
- Red Deck: +1 Discard.
- Blue Deck: +1 Hand.
- Green Deck: Start with more money.
- Yellow Deck: Start with a specific Joker.
- Black Deck: Start with a specific card modification.