Call of Duty: Infinite Warfare offers several difficulty settings to cater to all player skill levels. These include Recruit, Regular, Hardened, and Veteran. For a first playthrough, 'Regular' offers a balanced challenge, while 'Hardened' provides a more intense experience. 'Veteran' is recommended for experienced players seeking the ultimate test of skill and patience, as enemies are more aggressive, deal more damage, and your health regenerates slower.

Beyond difficulty, the game also includes various accessibility options. These can be found in the 'Options' menu under 'Accessibility'. You can adjust subtitle size, colorblind modes, aim assist strength, and controller vibration. Take the time to explore these settings to create a comfortable and enjoyable gaming experience tailored to your individual needs. Don't be afraid to start on a lower difficulty and increase it as you become more proficient with the game's mechanics.