Dead Cells
Dead Cells

Your First Run: What to Expect

Start your first Dead Cells run by understanding base mechanics, runes, and how the Dead Man's Bag works. Learn about enemy tactics and biome progression.

·Multi-source verified (69/69)

Your First Run: What to Expect

This guide covers all new content from the Rise of the Giant and Bad Seed DLCs, offering a comprehensive walkthrough. It includes a large basics section, a game progression flowchart, level guides, boss strategies, Blueprint locations, and an achievement/trophy guide. Navigate using the 'Next' buttons or the table of contents.

This guide offers:

  • A large basics section answering many Dead Cells questions.
  • A game progression flowchart.
  • Guides to each level in the game.
  • Boss strategy guides for every boss.
  • Location guides for every Blueprint.
  • Achievement/trophy guide.

Main sections of this guide:

Basics

  • Combat Mechanics and Techniques
  • Stats, Equipment and Mutations
  • Runes
  • Mini-Map and Points of Interest
  • Enemy Tactics

Walkthrough

  • Game Progression Flowchart

Biomes

  • Prisoners' Quarters
  • Promenade of the Condemned
  • Toxic Sewers
  • Dilapidated Arboretum
  • Ramparts
  • Ancient Sewers
  • Prison Depths

At the start of Prisoners' Quarters, a Dead Man’s Bag spawns containing some gold from your last run. The amount depends on your current level of Gold Reserves, with any gold above this limit being lost. A maximum of one outfit and one item blueprint may be randomly dropped by enemies.