Overview: Powerful, temporary buffs to S.P.E.C.I.A.L. stats, skills, or damage resistance. Most chems carry a risk of addiction, which incurs negative stat penalties until cured.
- Jet: Slows down time.
- Psycho: Increases damage resistance and damage output.
- Med-X: Increases damage resistance.
- Buffout: Increases Strength and Endurance.
- Mentats: Increases Intelligence and Perception.
- Fixer: Cures all addictions.
Strategy: Use chems strategically for difficult encounters. Be mindful of addiction risk; carry Fixer or visit a doctor to cure it. The 'Chem Resistant' perk can reduce addiction chance.