Beyond takedowns, Rex 'Power' Colt possesses a range of combat and survival skills that make him a formidable opponent in direct engagements. These skills are also unlocked automatically as you gain experience, enhancing your overall effectiveness in firefights.

Key combat and survival skills include:
- Increased Health & Armor: Rex's cybernetic enhancements naturally increase his durability, allowing him to withstand more damage.
- Faster Healing: Syringes become more potent and heal Rex more quickly.
- Weapon Proficiency: Rex handles all weapons with expert precision, reducing recoil and improving accuracy.
- Explosive Resistance: Reduced damage from grenades and other explosions.
- Sprint Reload: The ability to reload your weapon while sprinting, maintaining mobility in combat.
- Last Stand: A temporary invulnerability period after taking fatal damage, allowing you to get a few last shots in or find cover.