San Andreas features numerous unique and rare vehicles, some of which are hidden or only spawn under specific conditions. Finding these can be a rewarding experience for collectors and provide advantages in missions or races.

- Bullet: A rare sports car, often found in Las Venturas or after completing certain races.
- Hotknife: A classic hot rod, unlocked after achieving all gold medals at the Driving School.
- Hydra: A vertical take-off and landing (VTOL) jet, found at the abandoned airstrip after completing the 'Vertical Bird' mission.
- Hunter: An attack helicopter, found at the abandoned airstrip after achieving all gold medals at the Flight School.
- Rhino: A tank, found at the abandoned airstrip after achieving all gold medals at the Driving School, or can be stolen from military bases.
- Monster: A monster truck, found in the Badlands or after completing the '8-Track' race.
- BF Injection: A dune buggy, found at Bone County or after winning the '8-Track' race.
Many unique vehicles are tied to completing schools or specific missions. Keep an eye out for them, as they often offer superior performance or unique capabilities. Storing these rare vehicles in your garage will ensure they are saved and available for future use. Some vehicles, like the Rhino and Hunter, are incredibly powerful and can make certain missions trivial.