After the initial cutscene, you'll be in Ken Rosenberg's office. Simply walk up to him to trigger the next cutscene. He'll explain the disastrous drug deal and the need to recover the money and drugs. This conversation sets the stage for your future endeavors in Vice City. Pay attention to the dialogue, as it provides crucial context for the unfolding story.
Once the cutscene concludes, you'll be free to explore the immediate area. Take a moment to familiarize yourself with the controls if you haven't already. Your first safe house, the Ocean View Hotel, is just a short walk away, offering a place to save your game and change clothes.