Beyond standard weapons, Hotline Miami 2 features a few throwable items and special equipment that can turn the tide of battle. These are often found in specific levels or are character-specific.

| Item | Description | Strategy |
|---|---|---|
| Brick / Bottle | Common environmental objects. Can be picked up and thrown. | Excellent for stunning enemies from a distance, allowing you to close in for a melee kill or knockout. Can also kill weaker enemies. |
| Molotov Cocktail | Explosive incendiary device. Creates a pool of fire. | Devastating for clearing groups of enemies or denying an area. Be careful not to catch yourself in the blast. |
| Grenade | Explosive device. High damage in a small radius. | Similar to Molotovs, but with a direct explosion. Good for clearing fortified positions or groups. |
| Door | Not an item, but an interactive environmental element. | Opening a door into an enemy will stun them, allowing for an easy takedown. Crucial for stealth and crowd control. |
Always be aware of your environment. Many levels offer throwable objects that can be just as effective as a weapon in the right hands.