Beyond combat gear and consumables, Like a Dragon: Ishin! features several key items and collectibles that serve different purposes, from advancing the story to unlocking new content.

Key Items:
- Story-Related Items: These are automatically acquired during main quests and are essential for progression. They cannot be sold or discarded.
- Quest Items: Specific items required for sub-stories or other side activities.
- Licenses/Permits: Unlock access to certain areas or activities (e.g., fishing license).
- Maps: Reveal more of the city on your mini-map.
Collectibles:
- Virtue Orbs: Small glowing orbs found throughout the environment. Collecting them grants Virtue.
- Wanted Men Posters: Posters of criminals that, when found, unlock bounties to hunt them down.
- Cat/Dog Food: Used to befriend stray animals for Another Life.
- Cooking Ingredients: Used in Another Life for cooking.
- Fishing Bait: Used for fishing.
Always check your inventory for new key items, especially if you're stuck on a quest. Many collectibles contribute to completion lists and can unlock valuable rewards. Exploring thoroughly and interacting with the environment will help you discover many of these hidden gems.