Chapter 3 introduces tiles like the Storm Temple, which zaps enemies on adjacent tiles, and Chrono Crystals, which accelerate time for adjacent tiles. These can be used to create powerful synergies. For example, placing a Storm Temple next to a River can create a powerful lightning storm that damages all enemies on the path.
Consider using the Oblivion card strategically to remove problematic tiles or to clear space for better combinations. The Ancestral Crypt, when unlocked, provides a significant HP boost but also increases the difficulty of adjacent tiles. Balance risk and reward carefully.