Power combos are a cornerstone of Mass Effect 3's combat system, allowing you to deal massive damage by combining certain biotic and tech powers. A combo consists of a 'primer' power that sets up an enemy, and a 'detonator' power that triggers the explosion. Understanding which powers prime and detonate is essential for maximizing your damage output and clearing groups of enemies efficiently. Experiment with different combinations!

Common Power Combos:
- Biotic Explosion: Primer (Warp, Singularity, Stasis) + Detonator (Throw, Warp, Charge).
- Tech Burst: Primer (Incinerate, Overload, Cryo Blast) + Detonator (Overload, Incinerate, Disruptor Ammo).
- Fire Explosion: Primer (Incinerate, Incendiary Ammo) + Detonator (Concussive Shot, Throw).
- Cryo Explosion: Primer (Cryo Blast, Cryo Ammo) + Detonator (Concussive Shot, Throw).