Understanding the controls is paramount to surviving in Peace Walker. The game offers several control schemes, so experiment to find what feels most comfortable for you. The default 'Hunter' scheme is often recommended for its similarity to traditional third-person shooters, but 'Action' provides a more classic MGS feel. Key actions include:

- Movement: Analog Stick (PSP) / Left Stick (HD Collection)
- Camera: D-Pad (PSP) / Right Stick (HD Collection)
- Crouch/Prone: X (PSP) / A (Xbox) / Cross (PS)
- Action/CQC: Circle (PSP) / B (Xbox) / Circle (PS)
- Weapon/Item Select: L + D-Pad (PSP) / LB + D-Pad (Xbox) / L1 + D-Pad (PS)
- Aim/First-Person: R (PSP) / RT (Xbox) / R1 (PS)
- Fire/Use Item: Square (PSP) / X (Xbox) / Square (PS)
Mastering CQC (Close Quarters Combat) is vital for stealth and non-lethal takedowns. A quick tap of the CQC button will perform a throw, while holding it will initiate a chokehold. From a chokehold, you can interrogate enemies for intel, knock them out, or even use them as human shields. Experiment with these techniques early on.