Peace Walker offers a wide array of weapons, catering to both lethal and non-lethal playstyles. Developing and upgrading these weapons is crucial for tackling tougher missions and bosses.

Lethal Weapons:
- Assault Rifles (M16A1, AK-47): Versatile for mid-range combat. Good for engaging multiple targets.
- Machine Guns (M60, PKM): High rate of fire, excellent for suppressing enemies or dealing with armored targets.
- Shotguns (M37, SPAS-12): Devastating at close range.
- Sniper Rifles (M1C, SVD): Long-range precision.
- Rocket Launchers (M1 Bazooka, RPG-7): Essential for destroying vehicles and AI weapons.
- Grenades (Frag, Smoke, Stun): Area-of-effect weapons for various tactical situations.
Non-Lethal Weapons:
- Tranquilizer Pistols (Mk. 22, EZ Gun): Your primary tool for stealth and non-lethal takedowns.
- Tranquilizer Sniper Rifles (Mosin Nagant): Long-range non-lethal option.
- Stun Grenades: Temporarily incapacitate enemies.
- Sleep Gas Grenades: Put enemies to sleep in an area.
Each weapon can be upgraded multiple times, increasing its damage, accuracy, magazine size, and other stats. Prioritize upgrading your most frequently used weapons, especially your tranquilizer pistol for stealth runs and a powerful rocket launcher for vehicle battles.