Movement in Path of Exile 2 is primarily handled by left-clicking to move your character. Interact with objects and attack enemies by left-clicking on them. Your primary attack skill is typically bound to the left mouse button, while other skills are assigned to the right mouse button and keyboard hotkeys (Q, W, E, R, T). Experiment with different keybinds to find what feels most comfortable for your playstyle. Holding down Shift while attacking will make your character attack in place.
