After completing the main story, Persona 5 Strikers offers a robust amount of post-game content to keep you engaged:

- New Game+: Upon clearing the game, you can start a New Game+. You'll carry over your Bond Level, character levels, Personas, equipment, money, and items. This allows you to experience the story again with a significant advantage, making it easier to complete any missed Requests or challenges.
- Merciless Difficulty: New Game+ unlocks the 'Merciless' difficulty setting. This significantly increases enemy strength and aggression, providing a true challenge for veteran players. Rewards are also boosted on this difficulty.
- Powerful Requests: Several new, extremely challenging Requests become available in the post-game. These often involve fighting powerful versions of previous bosses or unique, high-level Shadows. Completing these can reward you with the best equipment and accessories in the game.
- Compendium Completion: Strive to complete your Persona Compendium by fusing every Persona. This is a long-term goal that requires extensive fusion and Persona hunting.
- Max Bond Level: Continue to grind Bond EXP to reach the maximum Bond Level, unlocking all Bond skills and making your party incredibly powerful.
The post-game offers a fantastic opportunity to fully power up your Phantom Thieves and conquer the ultimate challenges Persona 5 Strikers has to offer.