The Persona 5 cast brings a focus on status ailments, critical hits, and powerful elemental attacks, offering a more aggressive and tactical approach to combat.
- Ryuji Sakamoto (Captain Kidd): A powerful Electric magic user and physical attacker. His Ziodyne and God's Hand are strong. Build him with Sub-Personas that boost Electric damage, provide critical physical skills, or offer defensive buffs.
- Ann Takamaki (Carmen): A dedicated Fire magic user and status ailment inflictor. Her Agidyne and Dormina are excellent. Equip her with Sub-Personas that boost Fire damage, provide additional status ailments, or offer healing.
- Morgana (Zorro): A Wind magic user and primary healer. His Garudyne and Mediarahan are invaluable. Build him with Sub-Personas that boost Wind damage, provide additional healing, or offer defensive buffs.
- Yusuke Kitagawa (Goemon): A fast Ice magic user and physical attacker. His Bufudyne and Brave Blade are powerful. Equip him with Sub-Personas that boost Ice damage, provide speed buffs, or offer critical hit chance.
- Makoto Niijima (Johanna): A versatile Nuclear magic user and physical attacker, also capable of healing. Her Frei and Mediarama are useful. Build her with Sub-Personas that boost Nuclear damage, provide additional healing, or offer defensive buffs.
- Futaba Sakura (Necronomicon): A dedicated support character, providing invaluable buffs, debuffs, and healing. Her abilities are unique and crucial for difficult fights. Equip her with Sub-Personas that boost her healing, provide additional support skills, or offer defensive buffs.
- Haru Okumura (Milady): A powerful Psy magic user and physical attacker. Her Psio and Triple Down are strong. Build her with Sub-Personas that boost Psy damage, provide critical physical skills, or offer defensive buffs.
- Goro Akechi (Robin Hood): A versatile Light/Dark magic user and critical hit specialist. His Hamaon, Mudoon, and Megidolaon are potent. Build him with Sub-Personas that boost Light/Dark damage, provide critical hit chance, or offer status ailment infliction.