Inventory space is extremely limited, making efficient management vital. Hip Pouches are the most valuable upgrades, increasing your inventory slots. Prioritize carrying essential weapons, a stack of ammo for each, healing items, and one defensive item. Store non-essential items and puzzle pieces in Item Boxes, which are linked across all safe rooms. Don't carry too many key items unless you're actively using them. Plan your routes to minimize backtracking and maximize inventory efficiency.
