Combat in Resident Evil 6 emphasizes both firearms and melee attacks. Aim for weak points, typically the head, to conserve ammunition and deal maximum damage. When enemies are stunned, follow up with a powerful melee attack to finish them off or create space. The 'quick shot' (aim + fire without aiming down sights) is useful for crowd control or when you're overwhelmed. Don't forget about the 'counter' mechanic: when an enemy attacks, a prompt may appear, allowing you to perform a devastating counter-attack if timed correctly. Conserve ammo by prioritizing melee finishers.
