Resident Evil: Revelations uses an auto-save system, but also offers manual saving at specific points. The game will automatically save your progress at key moments, such as completing objectives, entering new areas, or after significant cutscenes. You'll see a small icon appear on screen to indicate an auto-save.
For manual saving, you'll need to locate Typewriter save points. These are typically found in safe rooms or before major boss encounters. Interacting with a typewriter will allow you to save your game to a specific slot. It's highly recommended to use these manual save points frequently, especially before challenging sections or if you're about to experiment with a new strategy. This allows you to revert to an earlier save if things go awry, preventing loss of significant progress.
While the auto-save is convenient, relying solely on it can be risky. Always make a manual save when you have the opportunity, particularly if you've collected valuable items or completed a difficult puzzle.