Back on the Queen Zenobia, Jill and Parker encounter the mutated Rachael Ooze. This is a recurring mini-boss that is fast, agile, and can regenerate if not defeated quickly. Your objective is to defeat Rachael and proceed through the ship. Rachael will chase you through several interconnected rooms. Focus fire on her exposed weak points (the yellow glowing areas) to deal significant damage. After a certain amount of damage, she will retreat. You'll need to pursue her through the ship, often encountering regular Ooze along the way. The final confrontation with Rachael takes place in a larger area, where you can use the environment to your advantage. Defeat her to complete this section and advance the story.
Rachael is a challenging enemy due to her speed and regeneration. Use powerful weapons like the shotgun or rifle. Grenades are also very effective. Don't waste ammo on her when she's not exposing her weak points. Keep moving and try to create distance to aim for her weak spots. If she grabs you, quickly mash the action button to escape. This encounter can be resource-intensive, so ensure you have enough ammo and healing items before engaging.