Your arsenal in Resident Evil is limited, making every shot count. Understanding the strengths and weaknesses of each weapon, and managing your precious ammunition, is vital.

Handgun:
- Description: Your starting weapon. Weak but has abundant ammo.
- Usage: Best for standard zombies, especially when aiming for headshots (though inconsistent). Good for conserving stronger ammo.
- Ammo: Handgun Ammo (found frequently).
Shotgun:
- Description: Powerful close-range weapon.
- Usage: Excellent for groups of zombies, Cerberus, and Hunters. Can decapitate zombies at close range.
- Ammo: Shotgun Shells (less common than Handgun Ammo).
Magnum:
- Description: The most powerful conventional firearm.
- Usage: Reserved for bosses and highly dangerous enemies like Hunters or Tyrant.
- Ammo: .357 Magnum Rounds (very rare).
Grenade Launcher (Jill Only):
- Description: Versatile weapon with different ammo types.
- Usage: Explosive Rounds for general damage, Flame Rounds for Plant 42, Acid Rounds for Hunters/Chimeras.
- Ammo: Grenade Rounds (Explosive, Flame, Acid - found in specific locations).
Combat Knife:
- Description: Melee weapon.
- Usage: Last resort, or for finishing off downed zombies to conserve ammo. Chris starts with it.
Rocket Launcher:
- Description: One-shot kill weapon.
- Usage: Provided for the final boss fight against the Tyrant.
- Ammo: Infinite (during final boss).