These temporary power-ups can turn the tide of battle:

- Serious Damage: Doubles your weapon damage for a limited time (usually 30 seconds). The screen will tint red. Save this for boss fights or extremely large enemy waves.
- Invulnerability: Makes you completely immune to all damage for a limited time (usually 30 seconds). The screen will tint blue. Incredibly useful for pushing through dangerous areas or surviving overwhelming odds.
- Serious Speed: Increases your movement speed significantly for a limited time. Useful for dodging, escaping, or quickly traversing large areas.
- Serious Sight: Highlights enemies and secrets through walls for a limited time. Less combat-focused but useful for exploration.
Power-ups are often found in secret areas or as rewards for clearing particularly tough encounters. Knowing when to activate them is a strategic decision that can save your life and conserve precious ammo. Don't waste them on small groups of enemies.