Key Items
These are unique, non-consumable items essential for story progression or unlocking new areas. Examples include the 'Rusty Key', 'Doctor's ID Card', 'Crank Handle', and various 'Map Fragments'. Always check your inventory for key items when stuck on a puzzle. Their descriptions often contain hints.

Crafting Components
Scattered throughout the world are various components used for crafting and upgrading. 'Scrap Metal' and 'Torn Cloth' are common and used for basic weapon repairs and health item crafting. 'Chemical Solvents' and 'Rare Herbs' are rarer, used for advanced upgrades or powerful healing concoctions. Always collect these, even if your inventory is tight, as they are invaluable.
Workbenches
These are designated locations where you can repair weapons, upgrade existing equipment (using crafting components), and craft basic consumables. Workbenches are typically found in safe rooms or specific story locations. Prioritize upgrading your primary weapons and armor as soon as you have the necessary components.
Consumables
These are single-use items that provide immediate benefits. 'First Aid Kits' restore a significant portion of health. 'Herbal Remedies' restore a small amount of health and reduce sanity drain. 'Ammo Packs' replenish ammunition for specific weapon types. 'Adrenaline Shots' temporarily boost damage. Always keep a healthy stock of these, especially before boss fights.