Slay the Spire
Slay the Spire

How to Beat Act 1 Bosses

Strategies for Act 1 bosses in Slay the Spire: Guardian, Slime Boss, and Hexaghost, focusing on their unique mechanics.

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The Act 1 bosses are your first major hurdle. They test your deck's ability to deal consistent damage and manage incoming attacks. Each boss has a distinct mechanic. The Guardian alternates between attacking and blocking. Slime Boss splits into smaller slimes, requiring AoE or burst damage. The Hexaghost has a multi-turn setup before a massive attack. Understanding their patterns and having a balanced deck is key to victory here.

Act 1 Bosses - Slay the Spire screenshot
Act 1 Bosses