Collecting Heart Pieces is a crucial side activity that directly increases Link's maximum health. For every four Heart Pieces you collect, Link gains an additional Heart Container. There are a total of 12 Heart Pieces scattered throughout Holodrum, meaning you can gain an extra three Heart Containers beyond those earned from bosses. Heart Pieces are often found as rewards for completing mini-games, solving environmental puzzles, or exploring hidden areas. Keep an eye out for suspicious spots, talk to all NPCs, and revisit areas with new items to uncover these vital health upgrades. A full list of locations is provided in a table below.

| Location | Requirement |
|---|---|
| Horon Village | Win the target practice game. |
| Woods of Winter | Use Roc's Feather to jump across gaps. |
| Sunken City | Change to Summer to dry up a pond. |
| Spool Swamp | Use Ricky to jump over holes. |
| Goron Mountain | Win the Goron Dance mini-game. |
| Western Coast | Bomb a cracked wall. |
| Subrosia | Trade for it in the Subrosian Market. |
| Samasa Desert | Dig in a specific spot. |
| Lost Woods | Navigate correctly. |
| North Horon | Use Moosh to cross a gap. |
| Ancient Ruins | Solve a season puzzle. |
| Remains of the Snake | Bomb a cracked wall. |