Heroes in AFK Arena generally fall into several key roles:

- Tanks: Absorb damage, protect allies, and often provide crowd control. Examples: Lucius, Brutus, Grezhul.
- Damage Dealers (DPS): Focus on dealing high damage to enemies. Can be single-target or area-of-effect. Examples: Shemira, Safiya, Eironn.
- Support: Heal allies, provide buffs, or debuff enemies. Examples: Rowan, Rosaline, Talene.
- Control: Specialize in crowd control (stuns, freezes, banishes) to disrupt enemy formations. Examples: Tasi, Mehira, Nara.
There are six main factions, each with unique strengths and weaknesses:
- Lightbearers: Balanced, strong healers and tanks.
- Maulers: Aggressive, high damage, often with self-buffs.
- Wilders: Strong crowd control and energy generation.
- Graveborn: Resilient, often summon minions, good sustain.
- Celestials: Powerful, versatile, often support or carry roles.
- Hypogeans: Debuff-focused, strong against specific targets.
Building teams with faction bonuses (e.g., 3 heroes of one faction + 2 of another) provides significant stat boosts, making faction synergy crucial.