These weapons offer unique functionalities or are acquired under specific circumstances.
- Combat Knife: Leon's primary melee weapon. Essential for parrying, stealth kills, and finishing off downed enemies. Can be upgraded for durability and power.
- Bolt Thrower: A silent weapon that fires bolts. Can be equipped with attachable mines for traps. Uses Bolts.
- Rocket Launcher: An extremely powerful, single-shot weapon that instantly kills most enemies and bosses. Can be purchased from the Merchant for a high price.
- Hand Grenade: Explosive grenade for area damage.
- Flash Grenade: Stuns enemies, instantly kills exposed Plagas, and disorients Garradors.
- Heavy Grenade: More powerful explosive grenade.