Part 36

Master 'Part 36' of The Binding of Isaac: Rebirth! Learn how to unlock powerful items like Loki's Horns and characters like Cain by defeating bosses and meeting specific in-game requirements.

Alright, let's dive into Part 36 of our Binding of Isaac: Rebirth guide. This section is all about unlocking some really cool stuff – new items and even new characters! It's mostly about meeting certain conditions, like defeating bosses or collecting specific amounts of money. Don't worry, we'll break down exactly what you need to do for each unlock.

Unlocking Items:

• Little C.H.A.D.: Just beat C.H.A.D. in The Basement. Easy peasy.
• Lil Chubby: You'll need to defeat Chub, Fistula, Gurdy, and Peep. These are all bosses you'll find in The Caves.
• Loki's Horns: This one requires you to take down Loki, Monstro II, and Mom. They're the main bosses of The Depths.
• Mom's Pill Bottle: Start using those Blood Donation Machines a lot! Keep donating blood, and eventually, you'll get this.
• Monstro's Tooth: For this, you'll need to beat The Duke of Flies, Gemini, Larry Jr., and Monstro. These are the bosses you'll find in The Basement.
• Spelunker: Simply complete both levels of The Caves.
• The Bean: Get ready to destroy a whole lot of... well, poo. Keep at it, and you'll unlock this.
• The Book of Belial: Defeat Mom's Heart.
• The Book of Sins: You need to defeat each of the Seven Deadly Sin mini-bosses at least once. Keep an eye out for them!
• The Common Cold: This is a bit specific. You need to collect both Roid Rage and The Virus in the same playthrough.
• The Lucky Foot: All you need is to have 55 cents (55c) at any point during a playthrough.
• The Nail: Defeat Mom's Heart three times.
• The Necronomicon: You'll need to use the 'XIII Death' Tarot Card a bunch of times.
• The Yum Heart: Get 7 heart containers at any point in a playthrough.

Unlocking Characters:

• Cain: Just like The Lucky Foot, you need to have 55 cents (55c) at any point in a playthrough.
• Eve: Make two deals with the Devil. This means buying something from a Devil's Room on two separate occasions.
• Judas: Defeat Mom's Heart.
• Magdalene: Similar to The Yum Heart, you need to have 7 heart containers at any point in a playthrough.

Unlocking Major Milestones:

• The Harbingers: To unlock this, you just need to defeat Mom.
• The Womb: This is Chapter 4! You unlock it by defeating Mom.

That covers the unlocks for this part! Keep playing, keep meeting these conditions, and you'll gradually get access to all this new content. It really changes up the game as you progress!