Left 4 Dead 2 Mutations Guide | AntMag

Q: What modes is Bleed Out available in Left 4 Dead 2?

Left 4 Dead 2 features various Mutations that alter gameplay modes and difficulty, changing weekly and detailed on the blog.

Q: What is the difficulty for Chainsaw Massacre in Left 4 Dead 2?

Left 4 Dead 2 features various Mutations that alter gameplay modes and difficulty, changing weekly and detailed on the blog.

Q: How do Defibrillators work in Death's Door Mutation?

Left 4 Dead 2 features various Mutations that alter gameplay modes and difficulty, changing weekly and detailed on the blog.

Q: What weapons are available in Four Swordsmen Mutation?

Left 4 Dead 2 features various Mutations that alter gameplay modes and difficulty, changing weekly and detailed on the blog.

Q: How do Special Infected spawn in Flu Season Mutation?

Left 4 Dead 2 features various Mutations that alter gameplay modes and difficulty, changing weekly and detailed on the blog.

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Bleed Out

Modes: Campaign, Versus
Difficulty: Insane!
Other details: No Health Kits, Defibrillators only provide temporary Health. Pills can cure the Black & White sickness.

Everyone's Health is ticking away in this game! There are no Health Kits. Pills and Adrenaline Shots are the only things that can boost one's Health. Due to the many Panic Events and lack of stable fitness, try to hurry!

Chainsaw Massacre

Modes: Campaign
Difficulty: Medium
Other details: Chainsaws have unlimited fuel.

Time to clean house in Campaign! The only weapons are Chainsaws that never run out of fuel, so start cutting! Be careful with those though; they can hurt!

Death's Door

Modes: Campaign
Difficulty: Hard
Other details: Incapacitation leads to death. There are fewer Defibrillators, and no Health Kits.

One should tread lightly in this Mutation; damage is permanent, and there's no coming back when all Health is lost! Witches are especially deadly here!

Flu Season

Modes: Campaign
Difficulty: Medium
Other details: Only Boomers, Spitters, and (bile-drawn) Common Infected spawn. Up to ten Special Infected can be present at a time. Boomers and Spitters are much faster.

Be sure to bring a raincoat; things will get messy in this Mutation! Consider bringing a long-range weapon to fight off the septic specials here!

Follow the Litre

Modes: Scavenge
Difficulty: Medium
Other details: Only one or two Fuel Cans can be active at a time.

Scavenge runs, only this time, only one set of Cans can be spawned at a time. The current Cans will always respawn (be brought back to life at a checkpoint after death) in the same location, so stay alert. Stay together; there's no excuse for wandering off!

Four Swordsmen

Modes: Campaign
Difficulty: Insane!
Other details: Only Katanas are available. Common Infected are absent.

Four Survivors against Special Infected in this melee brawl! The only weapon available is the ancient Katana. The Special Infected are much more numerous here, so stay alert!

Gib Fest

Modes: Campaign
Difficulty: Easy
Other details: Machine Guns have unlimited Ammo.

Cry some more in this Mutation with M60 Machine Guns! There's no need to worry about running out of ammo. There's also Magnum Pistols thrown in for good measure. No other Weapons are available, so start shooting!

Hard Eight

Modes: Campaign
Difficulty: Insane!
Other details: Two of each type of Special Infected can be present at a time.

More Special Infected? Will the pain in this Campaign never end?! Watch out for each Infected's twin!

Headshot (a shot that lands on the enemy's head, usually an instant kill)

Modes: Campaign
Difficulty: Hard
Other details: Only Headshots can kill Common Infected (along with fire and explosions).

Boom, Headshot! Aim true, since the only thing that can kill the Infected is a blow to the head. Special Infected can be killed normally.

Healing Gnome

Modes: Campaign
Difficulty: Hard
Other details: The Gnome is capable of healing the one who carries it.

Bleed out and Last Gnome on Earth in one! The only way to patch up is to carry Mr. Chompski, so be sure to share him amongst the group! Nobody's health is permanent either!

Healthpackalypse

Modes: Versus
Difficulty: Insane!
Other details: Health Kits and Consumables are unavailable.

No Healing in this dangerous Versus variant.

Hunting Party

Modes: Campaign
Difficulty: Hard
Other details: All Special Infected are Hunters.

Rats. Nothing but Hunters. At least it's good practice for Hunter-stops!

Iron Man

Modes: Realism
Difficulty: Insane!
Other details: Starting from a Safe Room is impossible. There are no Ammo Caches.

No continues or failures allowed in this Campaign! If everyone dies, they must start from the beginning all over again! Plus, the only way to refill on Ammo is to change guns; there are no Piles of bullets to make that Laser- guided gun last!

Last Gnome on Earth

Modes: Campaign
Difficulty: Medium
Other details: The Infected will focus their attacks on the Gnome carrier.

Gnome Chompski must be carried through the map to the rescue. Watch out for the Infected trying to get him! All the Common Infected will attack whoever is carrying the Gnome! The Gnome must be carried in the Safe Room to advance to the next level, and if it gets thrown somewhere that the Survivors can't get to, don't worry! He'll respawn somewhere safe!

Last Man on Earth

Modes: Single Player
Difficulty: Hard
Other details: No Bots. Common Infected are absent. Health Kits and Tier 2 Weapons are more common.

No allies! Oh shame! There are no Common Infected either, so the only beings on the field are the lonely Survivor and the hostile Special Infected. Though the Survivor can get back up after being incapacitated by a Special Infected, they are still extremely dangerous; an attack by a Special Infected often means a Health Kit lost!

Lone Gunman

Modes: Single Player
Difficulty: Insane!
Other details: No Bots. Only Common Infected, Boomers, and Boss Infected are present. No Primary Weapons, 9mm Pistols, or Melee Weapons. Common Infected hit much harder.

It's a Survivor against the world. And with just a single Magnum Pistol! The Infected are much deadlier, so be sure not to miss! And watch out for those Boss Infected...

Nightmare