of his health.

A complete guide to finding all 8 Serums in Silent Hill: Homecoming. Learn the exact locations in Town Hall, Grand Hotel, Dr. Fitch's Office, and more.

This guide details the locations of all 8 Serums in Silent Hill: Homecoming.

1. Serum 1
   Area: Town Hall (Shepherd's Glen)
   Location: South Room in Town Hall. Check the table in the back left portion of the room.
2. Serum 2
   Area: Grand Hotel
   Location: Room 408 (Restroom). After the cutscene with Pyramid Head on the fourth floor, go through Room 405 and 407 to emerge on the east side of the hall past the debris. Hack through the boards along the side of Room 408. Defeat the Swarm that attacks and pick this up from the medicine case on the sink.
3. Serum 3
   Area: Dr. Fitch's Office
   Location: Examination Room. Enter the room down the dark corridor at the end of Dr. Fitch's Office. Examine the locked case on the dresser inside. Leave the room with the flashlight off and defeat the four Nurses outside. Enter the room near the reception and collect the small key and the serum from the medical case on the shelf against the far wall.
4. Serum 4
   Area: Otherworld Doctor Fitch's Office
   Location: Hell Descent. When Alex first arrives in the area with the fans that have numbers on them, before pulling any levers, duck under Fan 3 and Fan 2. Behind Fan 2 is a table with a medical case containing this serum.
5. Serum 5
   Area: Rose Heights Cemetery
   Location: Founders Garden. After unlocking the east mausoleum with the Ceremonial Dagger, use the dagger to unlock the west mausoleum as well. Take this from the medical case on the right coffin inside.
6. Serum 6
   Area: Streets of Silent Hill
   Location: Alchemilla Hospital (outside). After exiting the Boiler Room through the west door, move to the west on Koontz Street then walk through the open gate in the middle of the outside portion of Alchemilla Hospital then open the medical case on the west bench to find this serum.
7. Serum 7
   Area: Overlook Penitentiary
   Location: Cell A15 in A Block. After fixing the power box with the cables in the Upper Guard Room, pull the second lever to the left next to the power box to open the door to Cell A15. Move along the catwalk to the west outside of the Upper Guard Room then leap over to Cell A15 and collect this item from the shelf off to the right inside of the cell.
8. Serum 8
   Area: Lair
   Location: Room 301. After rescuing Elle, take the Room 301 Key from the key rack in Room 321 then backtrack all the way to Room 301. Unlock the door and this serum will be in the back northeast corner in a medical case on a desk.