Find the Empire State Art Museum (ESAM) in Ultimate Spider-Man. Access the West ESAM sign area for the second Venom fight.
Location:
To reach the ESAM, start at the first intersection west of the Queensborough Bridge. Travel straight (North), passing one intersection. Stop at the next right (East) turn. The ESAM building is to the North, identifiable by its blue color, sculptures, and a glass dome on the roof.
Access Point for Venom Fight:
The specific area for your second fight with Venom is located to the left (West) under the West "ESAM" sign, at ground level.
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