Sheperding Wolves

First things first, you'll need to enter Lowtown at night. Once you're there, make your way to Sister Petrice. She'll kick off the quest 'Sheperding Wolves' for you. Just follow her down the alleyway.

You'll run into some Street Thugs pretty quickly. Take them out, then head over to Petrice's Safehouse. After a bit of a chat, you'll agree to escort Ketojan through the Undercity.

As you start moving out, watch out for Spiders that'll try to ambush you. There's a simple trap right between you and them, so be ready to deal with that.

When you get to the top of the stairs, you'll find a standard trap. Disarm it, and then take care of any more Arachnids lurking around.

Another standard trap is blocking your path to the west. Disarm it, and then head north.

After meeting up with Ketojan, you'll need to escort him through the rest of the spider-infested Undercity.

Keep an eye out for another standard trap between you and the next group of enemies. Disarm it and defeat the Spiders.

There's a standard trap just before the stairs and another one right at the top, before you encounter more Spiders.

Open the chest you find to the north, then go around the corner. You'll encounter a group of thugs. No matter what you do, you'll have to fight them. After the battle, loot the chest you find.