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How to Kill the Chainsaw Sisters in Chapter 6: To In Re4 Remake
Resident Evil 4 (Remake)

How to Kill the Chainsaw Sisters in Chapter 6: To In Re4 Remake

Learn how to defeat the dangerous Chainsaw Sisters in Chapter 6 of Resident Evil 4 (Remake). This guide covers strategies, weapon recommendations, and tips for survival.

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Learn how to defeat the dangerous Chainsaw Sisters in Chapter 6 of Resident Evil 4 (Remake). This guide covers strategies, weapon recommendations, and tips for survival.

Walkthrough
  1. 1
    When the cutscene ends, the Chainsaw Sisters will spawn close to you. Be ready to defend yourself immediately by shooting them in the head with a powerful weapon to stagger them, or by throwing a grenade in front of them.
  2. 2
    If you stagger both sisters while they are close together, you will have a window of opportunity to focus damage on one of them. Prioritize taking down one sister first to make the encounter easier.
  3. 3
    Be aware that other villagers will enter the building from the door behind you. Quickly kill them with headshots, as some may transform into tentacled enemies requiring additional shots.
  4. 4
    Constantly move around the building to avoid being cornered, especially while reloading.
  5. 5
    As the sisters approach, shoot them in the head. The effectiveness of this depends on your weapon and its upgrades. The W-870 Shotgun and SR M1903 Rifle are recommended powerful options at this stage.
  6. 6
    If you find yourself cornered and overwhelmed, you can parry the sisters' chainsaw attacks with your knife. This is a temporary measure as your knife will take damage and become unusable.
  7. 7
    Use grenades on groups of villagers if necessary and always watch your back to avoid grabs.
  8. 8
    Kite enemies to keep them at a distance.
  9. 9
    The key to this encounter is to keep shooting the sisters whenever possible. The longer they survive, the more villagers will flood the area, increasing the danger.
Tips
  • Staggering both sisters simultaneously with grenades or headshots provides a crucial opening to focus damage.
  • Concentrate your attacks on one sister at a time to reduce the number of threats more quickly.
  • Maintain constant movement to prevent being trapped, particularly during reloads.
  • Powerful weapons like the W-870 Shotgun and SR M1903 Rifle are effective for bringing down the sisters faster than your pistol.
  • Use your knife to parry chainsaw attacks only when absolutely necessary, as it is a limited resource.
  • Grenades can be useful for dealing with groups of regular villagers and can also damage the sisters.
  • Always be aware of your surroundings and watch your back for ambushes or grabs.

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