Part 1

Introduction and General Information (VCT1): This section details the guide's structure, provides an overview of Grand Theft Auto: Vice City Stories, technical data for different versions (PSP, PS Vita, PS2), game structure differences, new features, controls for various vehicles and actions (on foot, hand-to-hand, weapons, bicycles, swimming, cars, motorcycles, boats, jetskis, helicopters, planes, Rhino, Hunter), the main screen interface, game menus, law enforcement details, using Pay 'N' Spray, consequences of being Busted or Wasted, purchase icons, outfits, and common gameplay issues. It also includes advanced tips and a 100% completion checklist.

The West Side and Starfish Island (VCT2): This part focuses on the initial game areas. It covers starting the game, your safehouse, preparing for main story missions, exploring the surroundings, a tour of the West Side and Starfish Island, empire sites and small businesses, finding weapons and helpful items (Health, Body Armor, Police Bribe icons), specific weapons and items available in these areas, explanations and locations for Red Balloons and Unique Stunt Jumps (including PS2 exclusive jumps), and details on side missions like Ambulance, Firetruck, Vigilante, and Taxi missions. It also explains Rampages and lists those found on the West Side and Starfish Island (including PS2 exclusive rampages), introduces the Dirtbike Track, Playground on the Town, and PS2 exclusive content like Playground on the Dock and Rush!, and mentions the Yankee Method.

The Main Story Missions (VCT3): This section begins the walkthrough of the core story. The first mission detailed is "Cleaning House" (MSY1), assigned by Sgt. Jerry Martinez (JMT1).