Follow our comprehensive Fallout 4 walkthrough for The Secret of Cabot House quest, detailing every step from Parsons State Administration to Cabot House, including enemy encounters and crucial decisions.
Walkthrough
- 1Follow Jack to the asylum. Loot guards and Raiders.
- 2Enter the asylum, proceed north-east, and clear out Raiders. Be wary of Berserk Raiders.
- 3Continue north-east up stairs, clear Raiders, and search the north-west room for a First Aid Box.
- 4Loot the wall Safe [Expert] in the north-west room.
- 5Follow Jack south-west through a room with lockers, then into a room with Radroaches and crates.
- 6Continue down stairs, through an office, and into a room where Jack reunites with Eddie.
- 7Question Jack about Lorenzo. Grab the Charisma Bobblehead from the desk. Check Eddie's terminal.
- 8Follow Jack back to the office, then north-west to the chained door.
- 9Jack unlocks doors to the east leading to the garden. Clear out Raiders on the ground and scaffolding.
- 10Head up the scaffolding, through a hole in the wall, and through a door to Parsons State Insane Asylum.
- 11Make your way west, then north to find a room with Raiders, including another Berserker.
- 12Backtrack south and loot the [Advanced] room for chems and five creepy monkey dolls.
- 13Return north to the cafeteria ruins and head down a ramp to the east.
- 14Follow Jack west, then south into a room with more Raiders.
- 15Fight east through a hole in the wall, then down a ventilation shaft to the isolation chambers.
- 16Loot the isolation chambers: one has a First Aid Box and chems, another has a Suitcase [Novice].
- 17Loot the last room to the south for a Syringer Rifle.
- 18Go down a hole in the floor to the north, through an office, and into a hallway with Raiders.
- 19Loot the cell to the east for chems.
- 20Head to the western-most room to the south to find a floor Safe [Advanced].
- 21Follow Jack down the elevator to the basement.
- 22In the basement, follow Jack south into a stone chamber, then east into a control room.
- 23Lorenzo talks to Jack. Exterminate the Raiders in the interior containment area, including their leader, Lefty (who has serum doses).
- 24After the Raiders are dead, choose to side with Lorenzo (endless Serum) or Jack (unique weapon).
- 25If siding with Lorenzo: Push the button near his cell to let him out. Jack flees.
- 26Search Lorenzo's cell for a Massachusetts Surgical Journal.
- 27Follow Lorenzo to a sealed containment door, which he blasts open.
- 28Leave the asylum via the elevator.
- 29Return to Cabot House. The Sentry Bot outside is hostile.
- 30Enter the house and confront Jack. Your dialogue choices affect Eddie's and Jack's reactions and potential speech checks.
- 31Lorenzo arrives and attacks. You can follow his plan to kill the Cabot family if you haven't made peace with them via a speech check.
Tips
- Berserk Raiders are stronger in melee and more aggressive due to the serum. Engage them at range if possible.
- The Charisma Bobblehead is located on a desk in the office where Jack reunites with Eddie.
- Be sure to check Eddie's terminal for lore about the asylum's patients.
- The isolation chambers contain a Suitcase [Novice] and a Syringer Rifle.
- The basement contains a floor Safe [Advanced].
- When choosing between Lorenzo and Jack, consider the rewards: endless Serum for Lorenzo, or a unique weapon for Jack.
- If you choose to side with Lorenzo, you can find a Massachusetts Surgical Journal in his cell.
- Be prepared for a hostile Sentry Bot outside Cabot House upon your return.
- Dialogue choices at Cabot House can lead to speech checks with Eddie and Jack, influencing the situation.
- Choice between endless Serum (from Lorenzo) or a unique weapon (from Jack).
- Charisma Bobblehead
- Massachusetts Surgical Journal
- Experience points and loot from defeated enemies.
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