From Diamond City to the Boston Public Library

Start by fast-traveling to the Mass Pike Tunnel East. Head north around some rubble, then north-east around more rubble. Continue north-east to reach a road.

Look south to spot the ruined lobby of a building with a bare metal frame. Be prepared for a random encounter.

Navigate the dangers, then head through a door in the lobby (under a wall with a clock) to enter the Dartmouth Professional Building. Inside, you can find a Radroach, Glowing Fungus, some food, and a Stimpak in a desk.

Exit the Dartmouth Professional Building's lobby heading north-east, then turn east and south-east to go through a doorway into Layton Towers.

Pass through a fence and cross a parking lot. Turn south to find a Raider and a Machinegun Turret MK I on a barricade between two buildings. Destroy them.

Head through the red door of the barricade. To the west, you can go down heavily trapped stairs (Can Chimes, a Grenade Bouquet, and a Tripwire) to reach the depressed highway.

Alternatively, go east to find a yellow lift to the roof. Defeat two Raiders and their Attack Dog, loot a Steamer Chest, then head north-east over ruined brick-work, through a hole in a wall, and through a door into the interior of Layton Towers.

Inside Layton Towers, head north-east down a hallway with a ruined floor and kill Raiders in a room to the north-west.

Go through a hole in the wall to the north-east and head downstairs where more Raiders are. Make your way south-east, then south-west, then north-west to find them. Loot a Chem Box [Novice] and a Tool Case [Novice].

Continue north-west down stairs and murder your way south-east into a nursery to find a Duffle Bag and a Suitcase [Novice].

Proceed north-east through a bedroom, then a bathroom, before turning north-west and heading down a ramp through a hole in the floor.

Continue south-west into the stairwell. Descend stairs to reach the basement.

To find a Safe [Advanced], go up stairs to the north-east, turn south-east, and enter a small room behind a counter.

To obtain a Fusion Core, head south-east from the stairwell to a room with machinery.

Exit Layton Towers through a door to the south-west.

From the landing overlooking the parking lot, turn north-west to find Police Precinct 8 and the Boston Public Library.

Enter the ruins of Police Precinct 8 to the west. Head north past some cells, kill Radroaches, then enter the north-eastern most cell to find Bobby Pin Boxes, a Stimpak, and “Eddie Winter Holotape 8”.

Search a nearby office for the Precinct 8 Evidence Terminal to potentially get new map markers.

Head east across the street to the Boston Public Library.

On the western side of the building, find a locked small door [Advanced]. If you cannot pick the lock, save your game, equip your best Charisma gear, and talk to the intercom to the right.

Tell the voice you are an employee and attempt the speech check by guessing the six-digit ID number (123456). If unsuccessful, reload and try again. Passing the speech check makes the robots inside friendly.

Alternatively, go around to the northern side of the building to find a tunnel leading into Copely Station. This subway area has Super Mutants, a Nuka Cola Machine with Nuka Cola Quantums, and a Duffle Bag under a bench.

Once inside the library (preferably through the front door), disarm a Tripwire near the doorway and grab a Grenade Bouquet.

Take a left, and after a short wait, a security breach will occur with Super Mutants attacking. Defend the barricaded area with the robots and turrets.