Weapon Upgrades — Synergy Guide

Discover all the item synergies in Enter the Gungeon! Learn how they work, their effects, and how to activate them to gain powerful advantages in the Gungeon.

Hey there! So you're diving into the Gungeon and want to know about those cool item combos, huh? Let's talk about Synergies. Think of them as special power-ups that happen when you've got certain items equipped at the same time. You'll usually see a little light blue arrow pop up to let you know you've activated one. These were actually tweaked quite a bit in the Advanced Gungeons & Draguns Update. They made a bunch more, made them easier to get, and gave every single one a name. Plus, you can now check out what's synergizing in your Ammonomicon – just select an item and it'll highlight the others that are working together. ### Notes on Synergies Just a heads-up: if a synergy involves guns, any stat boosts it gives usually only apply to those specific guns. Sometimes, the synergy might only really work with one of the weapons involved. ### Synergy Factor This is a hidden stat that basically tries to give you a synergy if you haven't found one yet. It's a multiplier that affects the chances of getting an item that will trigger a synergy based on what you're currently carrying. It starts at 1.7999882 (so, about 1.8 times more likely) and goes down the more synergies you get during a run. It never goes up unless you start a new run or win the game. Here's a rough idea of how it changes: * 0 Synergies: 1.7999882x likelihood * 1 Synergy: 1.120989x likelihood * 2 Synergies: 1.02681x likelihood * 3 Synergies: 1.00829x likelihood After you've gotten a couple of synergies, this factor doesn't really impact things much anymore. Also, dropping a synergy item before opening chests won't change your Synergy Factor. One more thing: your progression matters! If you've reached The Forge at least 3 times, your starting Synergy Factor is 1.7999882. But if you're on a brand new save file, it actually starts higher, at 6.0 (meaning you're 6 times more likely to find a synergizing item compared to a random one). ### List of Synergies This is where the fun really begins! Here are some of the combos you can find: 360 Yes Scope * Items: Scope, A.W.P. OR Sniper Rifle * Effect: Spin around 360 degrees, and your next shot gets a 1.5x damage buff for 3 seconds. You can stack this buff up to six times if you keep spinning. Absent Minded * Items: The Membrane, Bouncy Bullets * Effect: The Membrane's shots will bounce 4 times and also become homing. Added Effect - Fire * Items: Alpha Bullet, Hot Lead * Effect: The very first bullet you fire from each magazine will be a fire bullet. Added Effect - Ice * Items: Alpha Bullet, Frost Bullets * Effect: The first shot from each magazine is guaranteed to be an ice bullet. Added Effect - Poison * Items: Alpha Bullet, Irradiated Lead * Effect: Your first shot of every magazine will be a poison bullet. Akey Breaky * Items: AKEY-47, Shelleton Key * Effect: The AKEY-47 gets a damage boost (10 extra damage per bullet) and infinite ammo. It'll also change its look to resemble a Shelleton. Just a heads-up, it won't be able to open locks by shooting them anymore. AI Assistant * Items: Roll Bomb, iBomb Companion App * Effect: Roll bombs will bounce around instead of exploding right away, and you can manually detonate them using the iBomb Companion App. Air Support * Items: Air Strike, ... (This synergy seems incomplete in the source data, but likely involves the Air Strike item.) Keep experimenting with different item combinations, and you'll discover even more awesome synergies!